Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.
Glycoprotein 330 (gp330) is an endocytic receptor expressed in the renal proximal tubules and some other absorptive epithelia, e.g., in the inner ear. The present study shows that the antifibrinolytic polypeptide, aprotinin, and the nephro- and ototoxic antibiotics, aminoglycosides, and polymyxin B...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118176 |
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