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The effects of thymic selection on the range of T cell cross-reactivity
Based on the results of a computational model of thymic selection, we propose a mechanism that produces the observed wide range of T cell cross-reactivity. The model suggests that the cross-reactivity of a T cell that survives thymic selection is correlated with its affinity for self peptides. In or...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1857316/ https://ncbi.nlm.nih.gov/pubmed/16285012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200535098 |
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