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Metabolic engineering of Escherichia coli for the production of l-valine based on transcriptome analysis and in silico gene knockout simulation

The l-valine production strain of Escherichia coli was constructed by rational metabolic engineering and stepwise improvement based on transcriptome analysis and gene knockout simulation of the in silico genome-scale metabolic network. Feedback inhibition of acetohydroxy acid synthase isoenzyme III...

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Bibliografski detalji
Glavni autori: Park, Jin Hwan, Lee, Kwang Ho, Kim, Tae Yong, Lee, Sang Yup
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857225/
https://ncbi.nlm.nih.gov/pubmed/17463081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702609104
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