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Prevention of human poliovirus-induced paralysis and death in mice by the novel antiviral agent arildone.

Arildone, a novel antiviral agent which blocks virion uncoating, was assessed for its ability to prevent paralysis and death in mice infected intracerebrally with a lethal dose of human poliovirus type-2 (strain MEF). Intraperitoneal administration of arildone suspended in gum tragacanth prevented p...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: McKinlay, M A, Miralles, J V, Brisson, C J, Pancic, F
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1982
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7159068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.6.1022
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