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Prevention of human poliovirus-induced paralysis and death in mice by the novel antiviral agent arildone.

Arildone, a novel antiviral agent which blocks virion uncoating, was assessed for its ability to prevent paralysis and death in mice infected intracerebrally with a lethal dose of human poliovirus type-2 (strain MEF). Intraperitoneal administration of arildone suspended in gum tragacanth prevented p...

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Detalhes bibliográficos
Main Authors: McKinlay, M A, Miralles, J V, Brisson, C J, Pancic, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC185714/
https://ncbi.nlm.nih.gov/pubmed/7159068
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