Prevention of human poliovirus-induced paralysis and death in mice by the novel antiviral agent arildone.

Arildone, a novel antiviral agent which blocks virion uncoating, was assessed for its ability to prevent paralysis and death in mice infected intracerebrally with a lethal dose of human poliovirus type-2 (strain MEF). Intraperitoneal administration of arildone suspended in gum tragacanth prevented p...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	McKinlay, M A, Miralles, J V, Brisson, C J, Pancic, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7159068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.6.1022
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