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Tumour necrosis factor α blockade induces an anti‐inflammatory growth hormone signalling pathway in experimental colitis

BACKGROUND: Neutralisation of tumour necrosis factor α (TNFα)restores systemic growth hormone function in patients with Crohn's disease, and induces mucosal healing. Anabolic effects of growth hormone depend on activation of the STAT5 transcription factor. Although it has recently been reported...

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Hlavní autoři: Han, X, Benight, N, Osuntokun, B, Loesch, K, Frank, S J, Denson, L A
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856672/
https://ncbi.nlm.nih.gov/pubmed/16777921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.094490
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