Anti‐inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization

Infliximab (IFX) has been used repeatedly in mouse preclinical models with associated claims that anti‐inflammatory effects are due to inhibition of mouse tumour necrosis factor (TNF)‐α. However, the mechanism of action in mice remains unclear. In this study, the binding specificity of IFX for mouse...

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Bibliografiske detaljer
Udgivet i:Clin Exp Immunol
Main Authors: Assas, B. M., Levison, S. E., Little, M., England, H., Battrick, L., Bagnall, J., McLaughlin, J. T., Paszek, P., Else, K. J., Pennock, J. L.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217947/
https://ncbi.nlm.nih.gov/pubmed/27669117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12872
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