Signal Transducer and Activator of Transcription 5b Promotes Mucosal Tolerance in Pediatric Crohn’s Disease and Murine Colitis

Growth hormone (GH) regulates anabolic metabolism via activation of the STAT5b transcription factor and reduces mucosal inflammation in colitis. Peroxisome proliferator-activated receptor (PPAR) γ suppresses mucosal inflammation and is regulated by GH through STAT5b. We hypothesized that the GH:STAT...

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Autores principales: Han, Xiaonan, Osuntokun, Bankole, Benight, Nancy, Loesch, Kimberly, Frank, Stuart J., Denson, Lee A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2006
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762482/
https://ncbi.nlm.nih.gov/pubmed/17148664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060186
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