CXCR3 and α(E)β(7) integrin identify a subset of CD8+ mature thymocytes that share phenotypic and functional properties with CD8+ gut intraepithelial lymphocytes

BACKGROUND: We previously demonstrated the existence of two distinct subsets of T cell receptor (TCR)αβ+CD8αβ+ single positive (SP) cells in human postnatal thymus which express the chemokine receptor CCR7 or CXCR3 and migrate in vitro in response to their specific ligands. AIM: To investigate wheth...

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Main Authors: Annunziato, F, Cosmi, L, Liotta, F, Lazzeri, E, Romagnani, P, Angeli, R, Lasagni, L, Manetti, R, Marra, F, Gerard, C, Petrai, I, Sbarba, P Dello, Tonelli, F, Maggi, E, Romagnani, S
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2006
Teme:
Gastrointestinal Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856348/
https://ncbi.nlm.nih.gov/pubmed/16368781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.077560
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