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Human T helper type 1 dichotomy: origin, phenotype and biological activities

The great variety of pathogens present in the environment has obliged the immune system to evolve different mechanisms for tailored and maximally protective responses. Initially, two major types of CD4(+) T helper (Th) effector cells were identified, and named as type 1 (Th1) and type 2 (Th2) cells...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Annunziato, Francesco, Cosmi, Lorenzo, Liotta, Francesco, Maggi, Enrico, Romagnani, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557671/
https://ncbi.nlm.nih.gov/pubmed/25284714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12399
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