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Cancer risks in LKB1 germline mutation carriers

BACKGROUND AND AIMS: Germline mutations in the LKB1 gene are known to cause Peutz‐Jeghers syndrome, which is an autosomal dominant disorder characterised by hamartomatous polyposis and mucocutaneous pigmentation. This syndrome is associated with an increased risk of malignancies in different organs...

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Detalhes bibliográficos
Main Authors: Mehenni, H, Resta, N, Park, J‐G, Miyaki, M, Guanti, G, Costanza, M C
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856321/
https://ncbi.nlm.nih.gov/pubmed/16407375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.082990
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