Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease

BACKGROUND AND AIMS: Epithelium derived interleukin (IL)‐15 signalling via IL‐15Rα is critical for the development, activation, and survival of intraepithelial lymphocytes (IEL). We aimed to better understand the IL‐15 driven effects on IEL underlying mucosal damage and lymphomagenesis in coeliac di...

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Main Authors: Sabatino, A Di, Ciccocioppo, R, Cupelli, F, Cinque, B, Millimaggi, D, Clarkson, M M, Paulli, M, Cifone, M G, Corazza, G R
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2006
Fag:
Coeliac Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856172/
https://ncbi.nlm.nih.gov/pubmed/16105889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.068684
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