Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease

BACKGROUND AND AIMS: Epithelium derived interleukin (IL)‐15 signalling via IL‐15Rα is critical for the development, activation, and survival of intraepithelial lymphocytes (IEL). We aimed to better understand the IL‐15 driven effects on IEL underlying mucosal damage and lymphomagenesis in coeliac di...

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Autors principals: Sabatino, A Di, Ciccocioppo, R, Cupelli, F, Cinque, B, Millimaggi, D, Clarkson, M M, Paulli, M, Cifone, M G, Corazza, G R
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2006
Matèries:
Coeliac Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856172/
https://ncbi.nlm.nih.gov/pubmed/16105889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.068684
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