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Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease

BACKGROUND—Lamina propria (LPLs) and intraepithelial (IELs) lymphocytes are markedly increased in coeliac mucosa, and are thought to play a crucial role in the generation of villous atrophy in coeliac disease (CD). However, the mechanisms by which they mediate the killing of enterocytes in this cond...

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Bibliographische Detailangaben
Hauptverfasser: Di, S, Ciccocioppo, R, D'Alo, S, Parroni, R, Millimaggi, D, Cifone, M, Corazza, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728419/
https://ncbi.nlm.nih.gov/pubmed/11511560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.3.380
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