Oestrogens inhibit interleukin 1β‐mediated nitric oxide synthase expression in articular chondrocytes through nuclear factor‐κB impairment

OBJECTIVES: To investigate the presence and functionality of oestrogen receptor α (ERα) in interleukin (IL)1β‐treated rabbit articular chondrocytes in culture, and to determine the mechanisms of 17β oestradiol (E2) effects on IL1β‐induced inducible nitric oxide synthase (iNOS) expression. METHODS: T...

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Bibliografiske detaljer
Main Authors: Richette, Pascal, Dumontier, Marie‐France, Tahiri, Khadija, Widerak, Magdalena, Torre, Antoine, Benallaloua, Mourad, Rannou, François, Corvol, Marie‐Therese, Savouret, Jean‐François
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2007
Fag:
Extended Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856006/
https://ncbi.nlm.nih.gov/pubmed/17068060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.059550
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