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Dual effects of 17ß-oestradiol on interleukin 1ß-induced proteoglycan degradation in chondrocytes

Objective: To determine whether 17ß-oestradiol (E2) modulates interleukin (IL) 1ß-induced proteoglycan degradation in chondrocytes, and to analyse the part played by metalloproteinases (MMPs) in this process. Methods: Primary cultured rabbit articular chondrocytes were prepared and treated with 10 n...

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Detalhes bibliográficos
Main Authors: Richette, P, Dumontier, M, Francois, M, Tsagris, L, Korwin-Zmijowska, C, Rannou, F, Corvol, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754890/
https://ncbi.nlm.nih.gov/pubmed/14722210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.006510
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