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Simvastatin reduces MMP-3 level in interleukin 1ß stimulated human chondrocyte culture
Objectives: Matrix metalloproteinases (MMPs) produced by chondrocytes play a role in the development of cartilage degradation in joint diseases. Moreover, inhibition of MMP secretion by macrophages accumulating in arteriosclerotic plaques would account for the plaque stabilising activity of statins...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1755052/ https://ncbi.nlm.nih.gov/pubmed/15194586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.009746 |
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