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Hyaluronan fragments activate nitric oxide synthase and the production of nitric oxide by articular chondrocytes

Chondrocyte CD44 receptors anchor hyaluronan to the cell surface, enabling the assembly and retention of proteoglycan aggregates in the pericellular matrix. Hyaluronan–CD44 interactions also provide signaling important for maintaining cartilage homeostasis. Disruption of chondrocyte–hyaluronan conta...

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Autors principals: Iacob, Stanca, Knudson, Cheryl B.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139231/
https://ncbi.nlm.nih.gov/pubmed/16181799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2005.08.011
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