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Hyaluronan fragments activate nitric oxide synthase and the production of nitric oxide by articular chondrocytes

Chondrocyte CD44 receptors anchor hyaluronan to the cell surface, enabling the assembly and retention of proteoglycan aggregates in the pericellular matrix. Hyaluronan–CD44 interactions also provide signaling important for maintaining cartilage homeostasis. Disruption of chondrocyte–hyaluronan conta...

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Autori principali: Iacob, Stanca, Knudson, Cheryl B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139231/
https://ncbi.nlm.nih.gov/pubmed/16181799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2005.08.011
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