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Amino Acid Residues Required for Maturation, Cell Uptake, and Processing of Translation Inhibitor Microcin C
Microcin C (McC), a peptide-nucleotide Trojan horse antibiotic, targets aspartyl-tRNA synthetase. We present the results of a systematic mutational study of the 7-amino-acid ribosomally synthesized peptide moiety of McC. Our results define amino acid positions important for McC maturation and cell u...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855700/ https://ncbi.nlm.nih.gov/pubmed/17158672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01609-06 |
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