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Intracellular Copper Does Not Catalyze the Formation of Oxidative DNA Damage in Escherichia coli

Because copper catalyzes the conversion of H(2)O(2) to hydroxyl radicals in vitro, it has been proposed that oxidative DNA damage may be an important component of copper toxicity. Elimination of the copper export genes, copA, cueO, and cusCFBA, rendered Escherichia coli sensitive to growth inhibitio...

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Autors principals: Macomber, Lee, Rensing, Christopher, Imlay, James A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855699/
https://ncbi.nlm.nih.gov/pubmed/17189367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01357-06
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