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Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx(-) mutants of Escherichia coli

Since the discovery of catalase, it has been postulated that aerobic organisms generate enough oxidants to threaten their own fitness and, in particular, their genetic stability. An alternative is that these enzymes exist to defend the cell against more-abundant oxidants imposed by external sources....

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書目詳細資料
Main Authors: Park, Sunny, You, Xiaojun, Imlay, James A.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166606/
https://ncbi.nlm.nih.gov/pubmed/15967999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502051102
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