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Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx(-) mutants of Escherichia coli

Since the discovery of catalase, it has been postulated that aerobic organisms generate enough oxidants to threaten their own fitness and, in particular, their genetic stability. An alternative is that these enzymes exist to defend the cell against more-abundant oxidants imposed by external sources....

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Detalhes bibliográficos
Main Authors: Park, Sunny, You, Xiaojun, Imlay, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166606/
https://ncbi.nlm.nih.gov/pubmed/15967999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502051102
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