Correlation of antibiotic resistance with Vmax/Km ratio of enzymatic modification of aminoglycosides by kanamycin acetyltransferase.

Kinetic data for the antibiotic-modifying enzyme kanamycin acetyltransferase AAC(6')-IV have been determined for five aminoglycoside antibiotics (amikacin, gentamicin C1a, kanamycin A, sisomicin, and tobramycin) and compared with close-interval determinations of the minimal inhibitory concentrations...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Radika, K, Northrop, D B
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1984
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6375556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.4.479
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