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Correlation of antibiotic resistance with Vmax/Km ratio of enzymatic modification of aminoglycosides by kanamycin acetyltransferase.
Kinetic data for the antibiotic-modifying enzyme kanamycin acetyltransferase AAC(6')-IV have been determined for five aminoglycoside antibiotics (amikacin, gentamicin C1a, kanamycin A, sisomicin, and tobramycin) and compared with close-interval determinations of the minimal inhibitory concentra...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC185556/ https://ncbi.nlm.nih.gov/pubmed/6375556 |
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