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The Anti-Trypanosoma cruzi Activity of Posaconazole in a Murine Model of Acute Chagas' Disease Is Less Dependent on Gamma Interferon than That of Benznidazole

We have investigated the influences of gamma interferon (IFN-γ) and interleukin-12 (IL-12) on the efficacy of posaconazole (POS) treatment of acute experimental infections with Trypanosoma cruzi; the standard drug, benznidazole (BZ), was used as a positive control. Wild-type (WT) mice infected with...

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Bibliografski detalji
Glavni autori: Ferraz, Marcela L., Gazzinelli, Ricardo T., Alves, Rosana O., Urbina, Julio A., Romanha, Alvaro J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855485/
https://ncbi.nlm.nih.gov/pubmed/17220408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01170-06
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