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Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
Mitochondrial antiviral signaling protein (MAVS) is an essential component of virus-activated signaling pathways that induce protective IFN responses. Its localization to the outer mitochondrial membrane suggests an important yet unexplained role for mitochondria in innate immunity. Here, we show th...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855380/ https://ncbi.nlm.nih.gov/pubmed/17438296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611506104 |
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