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Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
Mitochondrial antiviral signaling protein (MAVS) is an essential component of virus-activated signaling pathways that induce protective IFN responses. Its localization to the outer mitochondrial membrane suggests an important yet unexplained role for mitochondria in innate immunity. Here, we show th...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855380/ https://ncbi.nlm.nih.gov/pubmed/17438296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611506104 |
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