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Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway
The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons (PTCs). Seven genes (smg-1–7, for suppressor with morphological effect on genitalia) that are essential for NMD were originally identified in the nematode Caenorhabditis elegans, and orth...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855233/ https://ncbi.nlm.nih.gov/pubmed/17437990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.417707 |
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