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The Short Arm of Laminin γ2 Chain of Laminin-5 (Laminin-332) Binds Syndecan-1 and Regulates Cellular Adhesion and Migration by Suppressing Phosphorylation of Integrin β4 Chain

The proteolytic processing of laminin-5 at the short arm of the γ2 chain (γ2sa) is known to convert this laminin from a cell adhesion type to a motility type. Here, we studied this mechanism by analyzing the functions of γ2sa. In some immortalized or tumorigenic human cell lines, a recombinant γ2sa,...

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Detalhes bibliográficos
Main Authors: Ogawa, Takashi, Tsubota, Yoshiaki, Hashimoto, Junko, Kariya, Yoshinobu, Miyazaki, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855018/
https://ncbi.nlm.nih.gov/pubmed/17314405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0806
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