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The Short Arm of Laminin γ2 Chain of Laminin-5 (Laminin-332) Binds Syndecan-1 and Regulates Cellular Adhesion and Migration by Suppressing Phosphorylation of Integrin β4 Chain
The proteolytic processing of laminin-5 at the short arm of the γ2 chain (γ2sa) is known to convert this laminin from a cell adhesion type to a motility type. Here, we studied this mechanism by analyzing the functions of γ2sa. In some immortalized or tumorigenic human cell lines, a recombinant γ2sa,...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855018/ https://ncbi.nlm.nih.gov/pubmed/17314405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0806 |
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