The Short Arm of the Laminin γ2 Chain Plays a Pivotal Role in the Incorporation of Laminin 5 into the Extracellular Matrix and in Cell Adhesion

Laminin 5 is a basement membrane component that actively promotes adhesion and migration of epithelial cells. Laminin 5 undergoes extracellular proteolysis of the γ2 chain that removes the NH(2)-terminal short arm of the polypeptide and reduces the size of laminin 5 from 440 to 400 kD. The functiona...

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Main Authors: Gagnoux-Palacios, Laurent, Allegra, Maryline, Spirito, Flavia, Pommeret, Olivier, Romero, Christine, Ortonne, Jean-paul, Meneguzzi, Guerrino
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192378/
https://ncbi.nlm.nih.gov/pubmed/11352943
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