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Amino-terminal fragments of laminin γ2 chain retract vascular endothelial cells and increase vascular permeability

Laminin γ2 (Lmγ2) chain, a subunit of laminin-332, is a typical molecular marker of invading cancer cells, and its expression correlates with poor prognosis of cancer patients. It was previously found that forced expression of Lmγ2 in cancer cells promotes their invasive growth in nude mice. However...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Sato, Hiroki, Oyanagi, Jun, Komiya, Eriko, Ogawa, Takashi, Higashi, Shouichi, Miyazaki, Kaoru
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317827/
https://ncbi.nlm.nih.gov/pubmed/24238220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12323
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