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Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ3

Angiomodulin (AGM) is a member of insulin-like growth factor binding protein (IGFBP) superfamily and often called IGFBP-rP1 or IGFBP-7. AGM was originally identified as a tumor-derived cell adhesion factor, which was highly accumulated in blood vessels of human cancer tissues. AGM is also overexpres...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Komiya, Eriko, Sato, Hiroki, Watanabe, Naoko, Ise, Marii, Higashi, Shouichi, Miyagi, Yohei, Miyazaki, Kaoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101744/
https://ncbi.nlm.nih.gov/pubmed/24737780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.216
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