Nuclear Factor-κB, p38, and Stress-Activated Protein Kinase Mitogen-Activated Protein Kinase Signaling Pathways Regulate Proinflammatory Cytokines and Apoptosis in Human Placental Explants in Response to Oxidative Stress : Effects of Antioxidant Vitamins

Preeclampsia is a potentially fatal complication of human pregnancy characterized by hypertension, proteinuria, and edema. Placental oxidative stress is a key element in the pathogenesis of the syndrome and results in the release of a cocktail of factors, including proinflammatory cytokines and apop...

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Detalhes bibliográficos
Main Authors: Cindrova-Davies, Tereza, Spasic-Boskovic, Olivera, Jauniaux, Eric, Charnock-Jones, D. Stephen, Burton, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854947/
https://ncbi.nlm.nih.gov/pubmed/17456758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061035
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