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Trophoblastic Oxidative Stress and the Release of Cell-Free Feto-Placental DNA

Considerable quantities of cell-free fetal DNA circulate in the maternal blood during human pregnancy, but the origin of the DNA remains uncertain. Circumstantial evidence suggests the placenta is the principal source, so we tested the hypothesis that release occurs from the syncytiotrophoblast afte...

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Autors principals: Tjoa, May Lee, Cindrova-Davies, Tereza, Spasic-Boskovic, Olivera, Bianchi, Diana W., Burton, Graham J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698796/
https://ncbi.nlm.nih.gov/pubmed/16877342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060161
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