Interaction of metronidazole with DNA repair mutants of Escherichia coli.

It has been proposed that one of metronidazole's partially reduced intermediates interacts either with DNA to exert a bactericidal effect or with water to form acetamide. To test this hypothesis we have examined the effect of metronidazole on several mutants of Escherichia coli that are defective in...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Yeung, T C, Beaulieu, B B, McLafferty, M A, Goldman, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6367636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.65
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