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Interaction of metronidazole with DNA repair mutants of Escherichia coli.

It has been proposed that one of metronidazole's partially reduced intermediates interacts either with DNA to exert a bactericidal effect or with water to form acetamide. To test this hypothesis we have examined the effect of metronidazole on several mutants of Escherichia coli that are defecti...

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Autores principales: Yeung, T C, Beaulieu, B B, McLafferty, M A, Goldman, P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC185437/
https://ncbi.nlm.nih.gov/pubmed/6367636
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