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Interaction of metronidazole with DNA repair mutants of Escherichia coli.

It has been proposed that one of metronidazole's partially reduced intermediates interacts either with DNA to exert a bactericidal effect or with water to form acetamide. To test this hypothesis we have examined the effect of metronidazole on several mutants of Escherichia coli that are defective in...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: Yeung, T C, Beaulieu, B B, McLafferty, M A, Goldman, P
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1984
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6367636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.65
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