Interaction of metronidazole with DNA repair mutants of Escherichia coli.

It has been proposed that one of metronidazole's partially reduced intermediates interacts either with DNA to exert a bactericidal effect or with water to form acetamide. To test this hypothesis we have examined the effect of metronidazole on several mutants of Escherichia coli that are defective in...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Yeung, T C, Beaulieu, B B, McLafferty, M A, Goldman, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6367636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.65
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