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Effect of protein binding on simulated intravascular and extravascular kinetics of cefotaxime in an in vitro model.

The simulated intravascular and extravascular kinetics of cefotaxime were studied in an in vitro model to evaluate the effect of antibiotic protein binding in the "intravascular" and "extravascular" space. Intravascular fluid consisted of either phosphate-buffered saline, which has no cefotaxime bin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Peterson, L R, Van Etta, L L, Fasching, C E, Gerding, D N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1984
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.58
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