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Effect of protein binding on simulated intravascular and extravascular kinetics of cefotaxime in an in vitro model.

The simulated intravascular and extravascular kinetics of cefotaxime were studied in an in vitro model to evaluate the effect of antibiotic protein binding in the "intravascular" and "extravascular" space. Intravascular fluid consisted of either phosphate-buffered saline, which has no cefotaxime bin...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Peterson, L R, Van Etta, L L, Fasching, C E, Gerding, D N
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.58
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