Effect of protein binding on simulated intravascular and extravascular kinetics of cefotaxime in an in vitro model.

The simulated intravascular and extravascular kinetics of cefotaxime were studied in an in vitro model to evaluate the effect of antibiotic protein binding in the "intravascular" and "extravascular" space. Intravascular fluid consisted of either phosphate-buffered saline, which has no cefotaxime bin...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Peterson, L R, Van Etta, L L, Fasching, C E, Gerding, D N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.58
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