Effect of protein binding on simulated intravascular and extravascular kinetics of cefotaxime in an in vitro model.

The simulated intravascular and extravascular kinetics of cefotaxime were studied in an in vitro model to evaluate the effect of antibiotic protein binding in the "intravascular" and "extravascular" space. Intravascular fluid consisted of either phosphate-buffered saline, which has no cefotaxime bin...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Peterson, L R, Van Etta, L L, Fasching, C E, Gerding, D N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.58
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