A carregar...
Tricyclic antidepressants block N-methyl-D-aspartate receptors: similarities to the action of zinc.
1. Using the radioligand [3H]-MK801, we have examined drug interactions with the phencyclidine recognition site of the N-methyl-D-aspartate receptor. 2. The tricyclic antidepressants desmethylimipramine and imipramine inhibited [3H]-MK801 binding with IC50 values of 7.4 and 22.5 microM, respectively...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1988
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1854115/ https://ncbi.nlm.nih.gov/pubmed/2905906 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|