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Inhibition by ketoconazole of mitogen-induced DNA synthesis and cholesterol biosynthesis in lymphocytes.

The effects of ketoconazole on mitogen-induced DNA synthesis and cholesterol biosynthesis in human and murine lymphocytes have been examined. Ketoconazole concentrations which do not affect cell viability (0.1 to 10 micrograms/ml) in culture led to a dose-dependent inhibition of DNA synthesis, as me...

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Detalles Bibliográficos
Autores principales: Buttke, T M, Chapman, S W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1983
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC185359/
https://ncbi.nlm.nih.gov/pubmed/6316842
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