Inhibition by ketoconazole of mitogen-induced DNA synthesis and cholesterol biosynthesis in lymphocytes.

The effects of ketoconazole on mitogen-induced DNA synthesis and cholesterol biosynthesis in human and murine lymphocytes have been examined. Ketoconazole concentrations which do not affect cell viability (0.1 to 10 micrograms/ml) in culture led to a dose-dependent inhibition of DNA synthesis, as me...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Buttke, T M, Chapman, S W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.4.478
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