Tumor Necrosis Factor-α Mediates Orthopedic Implant Osteolysis

Osteolysis complicating arthroplasty reflects progressive generation of implant-derived wear particles, which prompt an inflammatory reaction attended by recruitment of osteoclasts to the prosthesis-bone interface. To identify a soluble mediator of peri-prosthetic osteolysis we first showed that imp...

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Autores principales: Merkel, Kurt D., Erdmann, Jeanne M., McHugh, Kevin P., Abu-Amer, Yousef, Ross, F. Patrick, Teitelbaum, Steven L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1999
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853441/
https://ncbi.nlm.nih.gov/pubmed/9916934
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