Papillary Thyroid Carcinoma Oncogene (RET/PTC) Alters the Nuclear Envelope and Chromatin Structure

Current evidence suggests the papillary thyroid carcinoma oncogene (RET/PTC) generates papillary thyroid carcinomas in one genetic step. We tested a resulting prediction that RET/PTC expression in thyroid epithelium should be sufficient to cause the changes in nuclear morphology diagnostic of this t...

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Autors principals: Fischer, Andrew H., Bond, Jane A., Taysavang, Panya, Battles, O. Eugene, Wynford-Thomas, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 1998
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853418/
https://ncbi.nlm.nih.gov/pubmed/9811335
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