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Pathological and Physiological Double-Strand Breaks : Roles in Cancer, Aging, and the Immune System

Pathological agents such as ionizing radiation and oxidative free radicals can cause breaks in both strands of the DNA at a given site (double-strand break). This is the most serious type of DNA damage because neither strand is able to provide physical integrity or information content, as would be t...

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Detalles Bibliográficos
Autor principal: Lieber, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853386/
https://ncbi.nlm.nih.gov/pubmed/9811320
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