Chargement en cours...

GPR40 is Necessary but not Sufficient for Fatty-Acid Stimulation of Insulin Secretion in Vivo

Long-chain fatty acids amplify insulin secretion from the pancreatic beta cell. The G protein-coupled receptor GPR40 is specifically expressed in beta cells and is activated by fatty acids. Loss of function of GPR40 was shown to markedly inhibit fatty-acid stimulation of insulin secretion in vitro....

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Latour, Martin G., Alquier, Thierry, Oseid, Elizabeth, Tremblay, Caroline, Jetton, Thomas L., Luo, Jian, Lin, Daniel C.-H., Poitout, Vincent
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853382/
https://ncbi.nlm.nih.gov/pubmed/17395749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db06-1532
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!