The Free Fatty Acid Receptor G Protein-coupled Receptor 40 (GPR40) Protects from Bone Loss through Inhibition of Osteoclast Differentiation

The mechanisms linking fat intake to bone loss remain unclear. By demonstrating the expression of the free fatty acid receptor G-coupled protein receptor 40 (GPR40) in bone cells, we hypothesized that this receptor may play a role in mediating the effects of fatty acids on bone remodeling. Using mic...

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Bibliografiske detaljer
Main Authors: Wauquier, Fabien, Philippe, Claire, Léotoing, Laurent, Mercier, Sylvie, Davicco, Marie-Jeanne, Lebecque, Patrice, Guicheux, Jérôme, Pilet, Paul, Miot-Noirault, Elisabeth, Poitout, Vincent, Alquier, Thierry, Coxam, Véronique, Wittrant, Yohann
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585087/
https://ncbi.nlm.nih.gov/pubmed/23335512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429084
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