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STRUCTURAL BASIS FOR THE ACTIN-BINDING FUNCTION OF MISSING-IN-METASTASIS

The adaptor protein missing-in-metastasis (MIM) contains independent F- and G-actin-binding domains, consisting respectively of an N-terminal 250-aa IRSp53/MIM homology domain (IMD) and a C-terminal WASP-homology domain 2 (WH2). We determined the crystal structures of MIM’s IMD and that of its WH2 b...

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Detalhes bibliográficos
Main Authors: Lee, Sung Haeng, Kerff, Frederic, Chereau, David, Ferron, François, Klug, Alexandra, Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853380/
https://ncbi.nlm.nih.gov/pubmed/17292833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.12.005
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